The Silent City — Elisabeth Vonarburg

Built as a refuge from a war-ravaged world outside, THE SILENT CITY is the final stronghold of science and knowledge. A self-perpetuating technology maintains the City in which only a handful of humans survive, despite rejuvenation treatments and cybernetics. Into this doomed world Elisa is born, child of her father's obsession with creating a human form with the ability to self-heal. Elisa devotes herself to her father's cause...until she begins to see the truth about the City and its occupants. Rebelling against her father/lover, Elisa discovers her unique gift for changing herself and the world around her. But time is running out. The human race is threatened by a virus that prevents the conception of male babies -- and women bear the blame. Elisa must determine her future...and the future of humanity.