DEA agent Art Keller, who makes a fatal mistake as an idealistic rookie. On his first posting, to Culiacan, Mexico, capital of the drug trade, Art befriends the Barrera brothers. Their friendship will eventually turn into a personal vendetta of epic proportions when it is revealed that their uncle, Miguel, a member of the state police, is a drug kingpin. The cast also features an Irish hit man, a call girl, and a priest, as Winslow feverishly indicts the U.S. war on drugs, tracing flawed policies that have cost DEA agents their lives yet failed to stop the flow of drugs across the border.
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