House Corrino — Brian Herbert; Kevin J. Anderson

In subterranean labs on the planet Ix, cruel Tleilaxu overlords are busy manufacturing a synthetic form of melange known as amal. If amal can supplant the spice from Dune, Emperor Shaddam IV will gain absolute power. But if the plot of Imperial House Corrino succeeds, this madness may result in the end of space travel, the Imperium, and civilization itself. It is only Duke Leto Atreides, badly overmatched yet desperate to free the Ixians from their oppressors, who stands a chance of averting this cataclysmic tragedy....