The Housewife Blues — Warren Adler

A handsome advertising executive sweeps Jenny, a "nice" girl from the Midwest, off her feet while visiting and they are soon married. Afterwards, he spirits her away to the super-charged world of New York City. A control freak, he warns her to beware of strangers and avoid making friends. But she cannot repress her small town upbringing and instinctive innocence, eventually forming relationships with many of the quirky tenants in their brownstone building and entering into their complicated and sometimes tragic lives.
Jenny's journey of self-discovery from naiveté through disenchantment to eventual wisdom is wonderfully wrought and builds to an astonishing climax.